diff --git a/build/config/compiler/pgo/pgo.gni b/build/config/compiler/pgo/pgo.gni
index 9e9a0c524992a..02a2900ebabbe 100644
--- a/build/config/compiler/pgo/pgo.gni
+++ b/build/config/compiler/pgo/pgo.gni
@@ -19,13 +19,15 @@ declare_args() {
   # bad compile times.
   chrome_pgo_phase = 0
   if (!dcheck_always_on && is_official_build &&
-      # TODO(crbug.com/1052397): Remove chromeos_is_browser_only once
-      # target_os switch for lacros-chrome is completed.
       # TODO(crbug.com/1336055): Update this now-outdated condition with regard
       # to chromecast and determine whether chromeos_is_browser_only is
       # obsolete.
       (is_high_end_android || is_win || is_mac || is_fuchsia ||
-       (is_linux && !is_castos && !chromeos_is_browser_only))) {
+       (is_linux && !is_castos) ||
+       # TODO(crbug.com/1435082): Currently arm boards are not working.
+       # Enable this for arm boards, once the lab set up is fixed.
+       (is_chromeos_lacros && is_chromeos_device && target_cpu != "arm" &&
+        target_cpu != "arm64"))) {
     chrome_pgo_phase = 2
   }
 
diff --git a/build/toolchain/cros/BUILD.gn b/build/toolchain/cros/BUILD.gn
index c815e1ab2844a..12b82ee411f36 100644
--- a/build/toolchain/cros/BUILD.gn
+++ b/build/toolchain/cros/BUILD.gn
@@ -134,6 +134,7 @@ cros_toolchain("nacl_bootstrap") {
     cc = cros_nacl_helper_arm32_cc
     cxx = cros_nacl_helper_arm32_cxx
     ld = cros_nacl_helper_arm32_ld
+
     # Avoid accidental use of Arm64 sysroot because of SYSROOT
     # env variable set in ChromeOS builds.
     toolchain_args.sysroot = cros_nacl_helper_arm32_sysroot
@@ -278,6 +279,12 @@ if (also_build_lacros_chrome_for_architecture != "") {
       also_build_lacros_chrome_for_architecture = ""
       chromeos_is_browser_only = true
       use_clang_coverage = false
+
+      # Do not propagate AFDO settings from Ash build to Lacros build.
+      # Specifically, Lacros uses PGO by default, so this would
+      # conflict.
+      clang_use_default_sample_profile = false
+      clang_sample_profile_path = ""
     }
     if (!lacros_use_chromium_toolchain) {
       # These are args for the template.